Controlling biological pathways with synthetic molecules that respond to light, pressure, and magnetic fields
The broad objective of Prof. Trauner’s research is to demonstrate the awesome power of chemical synthesis with challenging target molecules and to use it toward the establishment of synthetic biological pathways. He is well known for his pioneering contributions to Optogenetics and Photopharmacology, using synthetic photoswitches to confer light-sensitivity to a broad range of targets. The chemical tools he developed are particularly useful in neuroscience and cell biology but also hold promise as precision therapeutics. Despite his extensive forays into biology and physiology Dr. Trauner remains an organic chemist at heart, as evidenced by the synthesis (and anticipation) of more than one hundred natural products.