Using DNA to direct the topology of commercial polymers.

Design of new protein folds.

Structure-function studies of membrane proteins.

Rational design of protein-protein interaction inhibitors.

Design of small-molecule sensors for cellular metals and reactive species.

Para-Hydrogen Induced Hyperpolarization of bioactive molecules.

Computational modeling of biomolecules.

Catalyst design for diversity-oriented olefin functionalization reactions for drug discovery.

Structures and reactions of oxocarbenium ions.